Tamoxifen / Nolvadex – Proper Labs
NOLVADEX® (tamoxifen citrate) Tablets, a nonsteroidal antiestrogen, are designed for oral administration and come in two strengths:
Inactive Ingredients: carboxymethylcellulose calcium, magnesium stearate, mannitol, and starch.
Chemically, NOLVADEX (tamoxifen citrate) is the trans-isomer of a triphenylethylene derivative. The chemical name is (Z)-2-[4-(1,2-diphenyl-1-butenyl) phenoxy]-N, N-dimethylethanamine 2 hydroxy-1,2,3-propanetricarboxylate (1:1). The structural and empirical formulas are:
Tamoxifen citrate has a molecular weight of 563.62, a pKa' of 8.85, an equilibrium solubility in water at 37°C of 0.5 mg/mL, and in 0.02 N HCl at 37°C, it is 0.2 mg/mL.
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